Regulatory sequence Totally Explained

Everything about Regulatory Sequence totally explained

A regulatory sequence (also called a regulatory region or a regulatory area) is a segment of DNA where regulatory proteins such as transcription factors bind preferentially. These regulatory proteins bind to short stretches of DNA called regulatory regions, which are appropriately positioned in the genome, usually a short distance 'upstream' of the gene being regulated. By doing so, these regulatory proteins can either recruit another protein complex, called the RNA polymerase. In this way, they control gene expression and thus protein expression. Regulatory sequences can also be found in messenger RNA, but they're generally not as well studied as those in DNA. They may be bound by RNA-binding proteins or RNAs (eg miRNAs)
Research to find all regulatory regions in the genomes of all sorts of organisms is under way.

Examples

For the insulin gene

Regulatory sequences for the insulin gene are:

negative regulatory element (NRE)

cAMP response element

CAAT enhancer binding (CEB)

G1Further Information

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